Related Experiment Videos
Thenoyltrifluoracetone induces lipid peroxidation in rat liver mitochondria
1Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino.
General Physiology and Biophysics
|June 1, 1993
Abstract:
Addition of thenoyltrifluoracetone to mitochondria oxidizing NAD-dependent substrates induced lipid peroxidation and uncoupling of oxidative phosphorylation. Butylated hydroxytoluene, an antioxidant, prevented accumulation of lipid peroxidation products but failed to prevent deenergization of the mitochondria.