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Growth and development of infants conceived by in vitro fertilization: a preliminary report
C Pruksananonda1, T Israsena, W Boonkasemsanti
1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Insights
This preliminary study followed 24 babies born via in vitro fertilization (IVF-ET) for one year. The children showed normal growth and development with no major congenital anomalies, supporting the safety of IVF-ET.
Area of Science:
- Reproductive Medicine
- Pediatrics
- Genetics
Background:
- In vitro fertilization with embryo transfer (IVF-ET) is a common assisted reproductive technology.
- Long-term outcomes for children conceived via IVF-ET require ongoing investigation.
- Assessing early growth and development is crucial for understanding IVF-ET's impact.
Purpose of the Study:
- To evaluate the growth and development of infants born after IVF-ET.
- To identify any congenital anomalies in this cohort.
- To establish preliminary safety data for IVF-ET at Chulalongkorn Hospital.
Main Methods:
- A prospective follow-up of the first 24 infants born after IVF-ET.
- One-year assessment of growth parameters and developmental milestones.
- Screening for major and minor congenital anomalies.
Main Results:
- All 24 infants demonstrated normal growth and development within the expected range.
- No major congenital anomalies were detected.
- Some minor anomalies were observed, requiring further monitoring.
Conclusions:
- Infants born following IVF-ET exhibit normal growth and development in the first year.
- IVF-ET appears safe, with no major congenital anomalies identified in this cohort.
- Long-term follow-up until school age is recommended to confirm sustained development.
Abstract:
This is a preliminary report on the first 24 babies born during the period of 1 year follow-up after IVF-ET in Chulalongkorn Hospital. Based on this study, our data suggests that these children have a normal range of growth and development. There was also no evidence of major congenital anomalies identified in spite of some minor ones. However, a need for more detail and on-going long-term follow-up at least until school age is being planned.