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The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin
A Lortie1, C Chiron, J Mumford
1Département de Neuropediatrie, Hôpital Saint-Vincent de Paul, Paris, France.
Neurology
|November 1, 1993
Abstract:
Although generally effective, various antiepileptic drugs have been reported on occasion to increase seizure frequency, result in seizure relapse, or elicit new types of seizures. Some seizure types and epilepsy syndromes appear more prone than others to exacerbation by a given drug. Vigabatrin is rarely associated with seizure worsening, and then mainly in patients with resistant generalized epilepsies.