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Visual acuity in patients with best vitelliform macular dystrophy
G A Fishman1, W Baca, K R Alexander
1Department of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois at Chicago.
Ophthalmology
|November 1, 1993
Summary
Best vitelliform macular dystrophy patients often experience visual acuity loss with age. Many older patients lose significant vision, impacting their ability to drive.
Area of Science:
- Ophthalmology
- Genetics
- Retinal Diseases
Background:
- Best vitelliform macular dystrophy (BVMD) is an inherited retinal disorder.
- It affects central vision and can lead to progressive visual impairment.
Purpose of the Study:
- To evaluate visual acuity loss in relation to age in patients with Best vitelliform macular dystrophy.
- To determine the correlation between age and visual function in BVMD.
Main Methods:
- Cross-sectional study of 47 patients diagnosed with Best vitelliform macular dystrophy.
- Inclusion criteria: recognizable BVMD phenotype; exclusion criteria: absent foveal changes or minimal pigmentary changes.
Main Results:
- A significant difference in visual acuity between eyes was observed in 64% of patients.
- Older patients showed a significant correlation with worse visual acuity.
- 76% of patients under 40 had 20/40 or better in at least one eye, while 74% over 30 had 20/100 or worse in at least one eye.
Conclusions:
- Patients with BVMD may retain good vision in one eye, but substantial monocular vision loss is common.
- No patient over 50 met the 20/40 criterion for driving, and only 20% over 40 did.