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Surfactant protein B deficiency: radiographic manifestations
T E Herman1, L M Nogee, W H McAlister
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis Children's Hospital Department of Radiology, Missouri 63110.
Pediatric Radiology
|January 1, 1993
Abstract:
Surfactant is a complex structure primarily composed of phospholipids, but containing essential proteins as well. Congenital deficiency of Surfactant Protein-B (SPB) has recently been documented for the first time in two siblings. The pathologic findings in these infants was that of congenital pulmonary alveolar proteinosis and the radiographic manifestations were strikingly similar to hyaline membrane disease.