[Cortisone in non-hemorrhagic stroke. An anterospective comparative study (author's transl)]

In an open, randomized anterospective, comparative study on encephalomalacias it was shown that with regard to the parameter of rehabilitation progress in the degree of paralysis, the patients treated with cortisone had a significantly better performance at the 5% level. The main point of attack of cortisone appears to be in the early phase of the insult (first 5 days). It seems unlikely that edema control is the only active principle. More probably this is an additional effect on cell metabolism. From these results it seems logical to continue to follow up the acute treatment of cerebral insult with cortisone and search for an optimal dosage and better confirmation.