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Malignant change in dermatitis artefacta

J C Alcolado1, K Ray, M Baxter

  • 1Department of Medicine, East Birmingham Hospital, UK.

Postgraduate Medical Journal
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

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Dermatitis artefacta, a self-inflicted skin condition, can rarely lead to squamous cell carcinoma. This case highlights the first reported death from malignant transformation of dermatitis artefacta, emphasizing the risks of chronic skin lesions.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Dermatitis artefacta is a self-induced skin condition characterized by chronic lesions.
  • Treatment typically involves avoiding self-trauma, topical steroids, and psychological support.
  • Unresolved lesions risk disfigurement, infection, and potential malignant transformation.

Observation:

  • A case report of an elderly woman with a 40-year history of excoriating a cholecystectomy scar is presented.
  • The chronic dermatitis artefacta lesion underwent malignant transformation.
  • The transformation was analogous to neoplastic changes seen in Marjolin's ulcers.

Findings:

  • The patient developed squamous cell carcinoma arising from the chronic self-inflicted lesion.
  • The squamous cell carcinoma metastasized widely.

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  • This represents the first reported fatality due to malignant transformation of dermatitis artefacta.

    • Implications:

    • Chronic skin lesions, including those from self-trauma, carry a risk of malignant transformation.
    • This case underscores the importance of recognizing and managing chronic wounds and self-inflicted dermatoses.
    • Further research into the oncogenesis of chronic inflammatory skin conditions is warranted.