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Related Experiment Videos

Modification of reflexes in normal and abnormal movements

R B Stein1, J F Yang, M Bélanger

  • 1Division of Neuroscience, University of Alberta, Edmonton, Canada.

Progress in Brain Research
|January 1, 1993
PubMed
Summary

Human locomotion involves complex neural and sensory inputs. Stimulating nerves can improve gait in patients with incomplete spinal cord injuries by modulating muscle reflexes.

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Area of Science:

  • Neuroscience
  • Biomechanics
  • Motor Control

Background:

  • Limb movement during locomotion is influenced by central nervous system circuits and sensory receptors.
  • Muscle reflexes are adaptively modulated during the step cycle and can be rapidly altered for different tasks like walking or running.
  • This reflex modulation is often impaired in patients with spasticity due to spinal cord or head injuries.

Purpose of the Study:

  • To investigate the modulation of muscle reflexes during human locomotion.
  • To explore the potential of nerve stimulation to improve gait in patients with neurological injuries.

Main Methods:

  • Observational analysis of limb trajectories during locomotion.
  • Investigation of cutaneous reflex modulation in normal subjects.

Related Experiment Videos

  • Assessment of nerve stimulation effects on muscle contraction and spasticity in patients.

    • Main Results:

    • Cutaneous reflexes can reverse from excitatory to inhibitory during the step cycle in normal subjects.
    • Stimulation of mixed nerves in patients can elicit muscle contractions and flexor reflex responses.
    • Nerve stimulation demonstrated a transient reduction in spasticity in antagonist muscles.

    Conclusions:

    • Muscle reflex modulation is crucial for normal locomotion and is significantly affected by neurological injury.
    • Nerve stimulation techniques show promise for enhancing gait and reducing spasticity in patients with incomplete injuries.
    • Simple stimulation systems may offer a viable approach to improve functional mobility in specific patient populations.