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Timing of exposures in ultrasonic hemorrhage of murine lung
C H Raeman1, S Z Child, E L Carstensen
1Department of Electrical Engineering, University of Rochester, NY 14627.
Ultrasound in Medicine & Biology
|January 1, 1993
Abstract:
Pressure thresholds for lung hemorrhage by exposure to low-temporal-average-intensity, pulsed ultrasound are of the order of 1 MPa. Earlier evidence suggested that ultrasound modifies the tissue over short periods of time in such a way that the nonthermal action of ultrasound is enhanced. Measurements of thresholds (1) for hemorrhage and (2) for penetration of the hemorrhage through the murine lung in which a given "on-time" was presented to the tissue over periods of time up to 3 min support the hypothesis.