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Opsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1
G H Cantor1, C H Pontzer, G H Palmer
1Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 991674-7040.
Veterinary Immunology and Immunopathology
|August 1, 1993
Abstract:
Antibody from cattle immunized with purified major surface protein-1 (MSP-1) was demonstrated to significantly enhance phagocytosis of Florida strain Anaplasma marginale by bovine macrophages in vitro. Serum immunoglobulin from individual MSP-1 immunized, protected cattle varied in ability to promote phagocytosis, however all sera were significantly opsonic as compared with sera from sham immunized control cattle.