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Related Experiment Video

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Endophthalmitis caused by Enterobacter cloacae

S A Milewski1, P Klevjer-Anderson

  • 1Ophthalmology Department, University of Connecticut, Storrs.

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|August 1, 1993
PubMed
Summary

Postoperative endophthalmitis, a severe complication of cataract surgery, can be caused by Enterobacter cloacae. This rare gram-negative infection led to phthisis bulbi despite aggressive treatment.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Cataract extraction with intraocular lens (IOL) placement is a common intraocular surgery.
  • Endophthalmitis is a devastating complication following cataract surgery.
  • Gram-negative bacterial infections pose a significant threat in postoperative endophthalmitis.

Observation:

  • A rare case of postoperative endophthalmitis caused by the gram-negative bacillus, Enterobacter cloacae, is reported.
  • This is the third reported instance of endophthalmitis attributed to Enterobacter cloacae.
  • The clinical course, treatment strategies, and laboratory identification of the organism are detailed.

Findings:

  • Enterobacter cloacae caused a severe case of endophthalmitis.

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  • Despite aggressive treatment including vitrectomy and intravitreal antibiotics, the infection was highly virulent.
  • The infection ultimately resulted in phthisis bulbi, a condition of the eye's shrinkage.

    • Implications:

    • This case expands the known spectrum of causative agents for gram-negative endophthalmitis.
    • It highlights the potential for aggressive and sight-threatening infections even with prompt and intensive treatment.
    • Understanding rare causative organisms like Enterobacter cloacae is crucial for managing endophthalmitis and improving patient outcomes.