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Synthesis and biological properties of 5-hydroxy-methylpyrimidines
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1993
Abstract:
Reduction of 4-arylamine-6-methyl-2-phenyl-5-pyrimidine carboxylic acid and its ethyl esters as well as 5,7-dihydrofuro (3,4-d)-pyrimidines resulted in obtaining some 4-arylamine-6-methyl-2-phenyl-5-hydroxymethylpyrimidines exhibiting strong immunomodulatory and cytostatic properties.