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Published on: September 14, 2016
Development of a shape vector that identifies critical forms assumed by human polymorphonuclear neutrophils during
1Division of Pediatric Hematology/Oncology, Childrens Hospital of Los Angeles, University of Southern California School of Medicine 90027.
Abstract:
Human polymorphonuclear neutrophils undergo characteristic shape changes that are critical to their ability to move and ingest their targets. We present here the construction of a simple shape vector, calculated from the coordinates of the cell perimeter, that can identify critical forms that a neutrophil assumes during the course of ameboid movement. The vector can be used to find neutrophils of a specific shape from the image analyzer data produced during a typical neutrophil tracking experiment.
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