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[The hand in hematologic diseases]

P N Scutellari1, C Orzincolo, F Franceschini

  • 1Istituto di Radiologia, Università degli Studi di Ferrara.

Minerva Medica
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

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Hand radiography reveals generalized diseases, particularly hematologic disorders like anemias and lymphomas. Specific radiographic patterns in the hand aid in diagnosing conditions such as thalassemia and sickle-cell disease.

Area of Science:

  • Radiology
  • Hematology
  • Oncology

Background:

  • Hand radiography is a valuable tool for detecting systemic diseases.
  • Hematologic disorders frequently manifest in the skeletal system, including the hands.

Purpose of the Study:

  • To review and discuss the radiographic patterns of the hand in various hematologic conditions.
  • To explore the pathogenesis of these hand-related radiographic findings.

Main Methods:

  • Review of radiographic patterns in patients with anemias, thalassemias, sickle-cell disease, lymphomas, multiple myeloma, and amyloidosis.
  • Utilized conventional radiography, xeroradiography, and digital radiography (PCR system) for imaging.
  • Focused on antero-posterior views of the hands to emphasize osseous and soft tissue details.

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Main Results:

  • Thalassemias show 100% hand involvement with diffuse osteopenia, widened marrow spaces, and thinning cortex.
  • Sickle-cell disease can present with a characteristic hand-foot syndrome ('cone-deformity').
  • Multiple myeloma (2.9% hand involvement) and non-Hodgkin lymphoma (0.2%) exhibit lytic lesions, with non-Hodgkin lymphoma patterns being nonspecific.

Conclusions:

  • Hand radiography is crucial for diagnosing and monitoring hematologic disorders.
  • Distinct radiographic findings in the hand correlate with specific hematologic conditions.
  • Advancements in digital radiography enhance diagnostic accuracy and patient safety.