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[Lymphoid infiltrates in the lung]

K Szalontai1, L Krenács, J Csanádi

  • 1Szent-Györgyi Albert Orvostudományi Egyetem Tüdögyógyászati Tanszék, Deszk.

Orvosi Hetilap
|November 7, 1993
PubMed
Summary

Pulmonary lymphoproliferative conditions present with varied lung symptoms. Radiologically, these conditions lack specific signs and can mimic other lung diseases like tuberculosis or tumors.

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Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • This study reviews pulmonary lymphoproliferative conditions diagnosed between 1980-1990 at the Department of Pulmonology, Albert Szent-Györgyi University of Medicine.
  • The review focused on 14 patients diagnosed with various lymphoproliferative disorders, including B-cell lymphomas, Hodgkin's lymphoma, and pleural pseudolymphoma.

Observation:

  • All patients presented with significant pulmonary symptoms.
  • Diagnoses were confirmed through histology, immunohistochemistry, and autopsy.
  • Two cases, one high-grade B-cell lymphoma and one angiocentric malignant lymphoma, were identified as primary pulmonary processes.

Findings:

  • No specific radiomorphological signs were identified to characterize pulmonary lympho-reticular infiltrations or differentiate primary from secondary involvement.
  • Low-grade non-Hodgkin's lymphomas often mimicked pulmonary tuberculosis on imaging.
  • High-grade lymphomas and Hodgkin's lymphomas presented radiologically similar to primary or multiple tumors.

Implications:

  • The findings highlight the diagnostic challenges in identifying pulmonary lymphoproliferative conditions due to non-specific radiological features.
  • Accurate diagnosis relies heavily on histological and immunohistochemical analysis.
  • Awareness of these varied presentations is crucial for clinicians managing patients with unexplained pulmonary symptoms.

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