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Virus-like particles in synovial fluids from patients with rheumatoid arthritis
G Stransky1, J Vernon, W K Aicher
1Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham.
British Journal of Rheumatology
|December 1, 1993
Abstract:
Based on the elevated expression of oncogenes in proliferating transformed-appearing synoviocytes we searched for the possible involvement of a viral agent in the pathogenesis of RA. We report the detection of virus-like particles with retroviral C type morphology in SF, which lack the typical morphologic as well as immunohistochemical features of the human T-lymphotropic and immunodeficiency viruses.