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Infective endophthalmitis following vitreoretinal surgery
A S Bacon1, C R Davison, B C Patel
1Moorfields Eye Hospital, London, UK.
Eye (London, England)
|January 1, 1993
Summary
Endophthalmitis after vitreoretinal surgery is rare but serious. Early diagnosis and targeted antibiotic prophylaxis, like ciprofloxacin, are crucial for better outcomes in these cases.
Area of Science:
- Ophthalmology
- Surgical Infections
Background:
- Endophthalmitis is a severe intraocular infection that can occur after vitreoretinal surgery.
- The incidence of endophthalmitis following explant surgery and vitrectomy varies.
Purpose of the Study:
- To describe cases of endophthalmitis post-vitreoretinal surgery.
- To identify risk factors and propose prophylactic strategies.
Main Methods:
- Retrospective case series of 11 patients with endophthalmitis after vitreoretinal surgery.
- Analysis of incidence rates for explant surgery and vitrectomy.
- Evaluation of prognostic indicators and diagnostic delays.
Main Results:
- Incidence of endophthalmitis was 0.19% after explant surgery and 0.15% after vitrectomy.
- Rapid onset of symptoms correlated with poor prognosis; delayed presentation (2-3 days) showed better outcomes.
- Posterior location of infection signs delayed diagnosis in some cases.
- Identifiable risk factors were present in 10 of 11 patients.
Conclusions:
- Intraocular instrumentation in retinal detachment repair may contribute to endophthalmitis risk.
- Speed of symptom onset is a key prognostic indicator.
- Supplementary antibiotic prophylaxis (ciprofloxacin or imipenem) is recommended for high-risk cases.