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[Dental amalgam: a toxicological evaluation]

D J Hansen1, P Hørsted-Bindslev, U Tarp

  • 1Aarhus Universitet, Institut for Miljø- og Arbejdsmedicin.

Ugeskrift for Laeger
|September 20, 1993
PubMed
Summary
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Dental amalgam fillings release small amounts of mercury, but exposure levels are below toxic limits. Allergic reactions are rare, and other claimed health issues lack strong evidence.

Area of Science:

  • Dental materials science
  • Toxicology
  • Environmental health

Context:

  • Dental amalgam, a widely used filling material, contains mercury, raising concerns about potential toxicity.
  • Review of recent literature to assess risks associated with mercury release from dental amalgam.
  • Occupational and general population exposure levels to mercury from dental sources are evaluated.

Purpose:

  • To evaluate the potential toxic effects of mercury from dental amalgam fillings.
  • To review current scientific literature on mercury absorption, transfer, and associated health concerns.
  • To assess the validity of claimed syndromes linked to amalgam fillings and guide clinical practice.

Summary:

  • Corrosion of dental amalgam releases mercury; estimated absorption in the Danish population (1-5 µg/24 hrs) is significantly below occupational and toxic levels.

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  • No evidence suggests avoiding amalgam during pregnancy due to placental mercury transfer.
  • Micromercurialism symptoms are non-specific, weakly documented, and potentially influenced by other factors; chelation therapy is not indicated. Allergic contact eczema is the only documented issue.
  • Impact:

    • Provides evidence that mercury exposure from dental amalgam is generally safe for the population.
    • Clarifies the lack of scientific basis for syndromes like micromercurialism linked to amalgam fillings.
    • Highlights that allergic contact eczema is the primary, albeit rare, adverse reaction to dental amalgam.