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Chronic mesenteric ischemia: evaluation with phase-contrast cine MR imaging
K C Li1, W S Whitney, C H McDonnell
1Department of Radiology, Stanford University School of Medicine, CA.
Radiology
|January 1, 1994
Summary
Phase-contrast cine MR imaging effectively measures superior mesenteric artery (SMA) blood flow. Changes in SMA blood flow after a meal best distinguish healthy individuals from those with SMA stenosis.
Area of Science:
- Vascular imaging
- Gastrointestinal diagnostics
- Medical physics
Background:
- Assessing superior mesenteric artery (SMA) blood flow is crucial for diagnosing gastrointestinal conditions.
- Noninvasive imaging techniques are needed to evaluate SMA hemodynamics in both fasting and postprandial states.
Purpose of the Study:
- To compare SMA blood flow in healthy volunteers and patients with SMA stenosis.
- To evaluate SMA blood flow in fasting and postprandial states using phase-contrast (PC) cine magnetic resonance (MR) imaging.
Main Methods:
- Ten healthy subjects and five patients with varying degrees of SMA stenosis were studied.
- SMA blood flow was measured using PC cine MR imaging after an overnight fast and at 15, 30, and 45 minutes after a standardized meal.
Main Results:
- Healthy volunteers showed a significant increase in SMA blood flow postprandially compared to fasting.
- The percentage change in SMA blood flow 30 minutes after food intake was the most effective parameter for differentiating healthy subjects from asymptomatic and symptomatic patients with SMA stenosis.
Conclusions:
- Cine PC MR imaging is a validated, noninvasive method for quantifying SMA blood flow.
- Postprandial changes in SMA blood flow measured by cine PC MR imaging can help identify and assess the severity of SMA stenosis.