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Cytotoxic activity of [Pt(pyr)(N-Etlm)Cl4]
M Massacesi1, Z Matovic, G Ponticelli
1Dipartimento di Chimica e Tecnologie Inorganiche e Metallorganiche Università di Cagliari, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|September 1, 1993
Abstract:
The [Pt(pyr)(N-Etlm)Cl4] complex, where pyr = pyrimidine and N-Etlm = N-ethylimidazole, previously prepared and characterized, showed an interesting cytotoxicity in vitro on the human ovarian carcinoma (A2780) and on his subline resistant to cis-platinum (A2780/CDDP), in comparison with cis-platinum and carboplatinum.