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Column-switching techniques for high-performance liquid chromatography of drugs in biological samples
P Campíns-Falcó1, R Herráez-Hernández, A Sevillano-Cabeza
1Departamento de Química Analítica, Facultad de Química, Universidad de Valencia, Burjassot, Spain.
Journal of Chromatography
|September 22, 1993
Abstract:
In recent years, an increasing number of publications have demonstrated the potential of column-switching techniques for the chromatographic separation, determination and preparative isolation of analytes from biological matrices. Column-switching systems greatly facilitate drug analysis, by on-line sample clean-up and trace enrichment, or by improving the analytical separative process. In this paper, the main applications of column-switching techniques to drug analysis in biological samples, are reviewed.