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[Progress and application of molecular genetics in the research of Mycobacterium tuberculosis]
1Department of Microbiology, University of Occupational and Environmental Health, Japan, Kitakyushu.
Kekkaku : [Tuberculosis]
|November 1, 1993
Abstract:
In the last decade, a great deal of advances in the genetics of Mycobacterium tuberculosis have been made by the introduction of new genetic technologies. In this review, a brief discussion of the progress in mycobacterial genetics, especially, gene cloning, development of host-vector systems, structural analysis of chromosomal DNA, plasmid DNA and mycobacteriophage DNA, IS element, and drug resistance mechanism was presented.