Neurologic complications of rheumatoid arthritis

Neurologic complications are common extraarticular manifestations of RA, involving both the peripheral and central nervous systems. Because RA patients suffer from pain, stiffness, and weakness, the detection of neurologic impairment is often difficult. Thus, close vigilance and thoughtful use of various diagnostic methods will help in the early diagnosis of cervical spine involvement, compression neuropathies, peripheral neuropathies, myopathies, and central nervous system involvement. Prompt and timely interventions may prevent permanent neurologic sequelae.