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Gardner syndrome and desmoid tumors
A Loccufier1, A Vanhulle, R Moreels
1Department of General, Thoracic and Vascular Surgery, Serruys Hospital, Ostend, Belgium.
Acta Chirurgica Belgica
|September 1, 1993
Summary
Complete surgical excision with radiotherapy can reduce desmoid tumour recurrence in Gardner's syndrome patients. Radiotherapy is a viable alternative when complete resection is not possible.
Area of Science:
- Oncology
- Surgical Oncology
- Radiation Oncology
Background:
- Desmoid tumours pose management challenges in Gardner's syndrome.
- Gardner's syndrome is associated with an increased risk of desmoid tumours.
Observation:
- Two Gardner's syndrome patients with desmoid tumours were studied.
- One patient underwent complete resection and radiotherapy; the other had incomplete resection without radiotherapy.
Findings:
- Complete surgical excision plus radiotherapy (4,000-6,000 rads) may decrease desmoid tumour recurrence.
- Tumour expansion was observed in the patient who refused radiotherapy after incomplete resection.
Implications:
- Multimodal treatment (surgery and radiotherapy) is recommended for desmoid tumours in Gardner's syndrome.
- Radiotherapy is a crucial alternative when complete surgical resection is not feasible.