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Association of delayed conception with caffeine consumption

E E Hatch¹, M B Bracken

¹Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT.

American Journal of Epidemiology

|December 15, 1993

Summary

High caffeine intake from beverages like coffee and tea is linked to longer time to conception. Women consuming over 300 mg daily had a significantly increased risk of delayed conception.

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Area of Science:

Reproductive Epidemiology
Environmental Health
Obstetrics and Gynecology

Background:

Fertility and conception timelines are crucial in reproductive health.
Understanding lifestyle factors influencing time to conception is important for public health.
Caffeine is a widely consumed psychoactive substance with potential reproductive effects.

Purpose of the Study:

To investigate the association between caffeine-containing beverage intake and the time required to achieve pregnancy.
To quantify the risk of delayed conception associated with varying levels of daily caffeine consumption.

Main Methods:

A cross-sectional study involving 1,909 married women in New Haven, Connecticut.
Data collected via interviews regarding time to conception and caffeine intake from beverages (coffee, tea, soft drinks).
Logistic regression and Cox proportional hazards models were used to analyze the relationship between caffeine intake and conception delay.

Main Results:

Caffeine consumption was associated with an increased risk of taking 1 year or more to conceive.
Odds ratios for delayed conception increased with higher caffeine intake levels (151-300 mg/day: 1.88; >300 mg/day: 2.24).
Higher caffeine intake (>300 mg/day) reduced per-cycle conception rates by 27%, and lower intake (<300 mg/day) by 10%.

Conclusions:

Daily caffeine intake from beverages is associated with a longer time to conception.
Higher levels of caffeine consumption correlate with a greater risk of delayed fertility.
Reducing caffeine intake may potentially improve conception rates for women trying to conceive.

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