Related Experiment Videos
Amaurosis fugax, Crohn's disease and the anticardiolipin antibody
S M Greenfield1, J P Teare, M W Whitehead
1Gastrointestinal Laboratory, Rayne Institute, St. Thomas' Hospital, London, UK.
Insights
Crohn's disease patients may experience blood clots due to clotting abnormalities. This study found anticardiolipin antibodies in a Crohn's patient, suggesting they contribute to this hypercoagulable state.
Area of Science:
- Gastroenterology
- Immunology
- Hematology
Background:
- Crohn's disease is linked to a hypercoagulable state, increasing risks of thromboembolic events.
- Platelet and clotting abnormalities are implicated in this hypercoagulability.
Abstract:
Crohn's disease is associated with a hypercoagulable state due to platelet or clotting abnormalities which may be responsible for the thromboembolic episodes seen in this condition. We report the occurrence of anticardiolipin antibodies in a patient with Crohn's disease who presented with Amaurosis fugax and suggest that these antibodies may be a further cause of the hypercoagulable state of Crohn's disease in some patients.