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Seizures and epilepsy in the elderly

M L Scheuer1, J Cohen

  • 1Department of Neurology, College of Physicians and Surgeons of Columbia University, New York.

Neurologic Clinics
|November 1, 1993
PubMed
Summary

The incidence of seizures and epilepsy increases significantly in older adults. This review covers causes, diagnosis, and antiepileptic drug pharmacology for this population.

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Area of Science:

  • Neurology
  • Geriatrics

Background:

  • Epilepsy and seizures are increasingly prevalent in the elderly population.
  • Limited evidence exists to guide treatment decisions in this demographic.

Purpose of the Study:

  • To review the causes and diagnostic evaluation of seizures in the elderly.
  • To discuss the pharmacology of antiepileptic drugs relevant to older adults.
  • To offer tentative treatment suggestions based on current knowledge.

Main Methods:

  • Literature review of recent data on elderly epilepsy.
  • Discussion of antiepileptic drug pharmacology.
  • Synthesis of information for treatment recommendations.

Main Results:

  • Seizure and epilepsy incidence and prevalence rise substantially in the elderly.
  • There is a lack of well-founded information for treatment decisions.
  • Antiepileptic drug pharmacology in the elderly requires careful consideration.

Conclusions:

  • Treatment for elderly patients with epilepsy requires careful consideration of drug pharmacology and potential interactions.
  • Tentative treatment suggestions are provided, highlighting the limitations of current knowledge.
  • Further research is needed to establish evidence-based treatment guidelines for epilepsy in the elderly.

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