Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Changes in coagulation in patients with sepsis]

G Alarcón1, P Fardella, G Conte

  • 1Departamento de Medicina, Servicio de Hematología, Hospital Clínico Universidad de Chile, Santiago de Chile.

Revista Medica De Chile
|May 1, 1993
PubMed
Summary

Sepsis frequently causes coagulation disorders, especially in patients with shock. These abnormalities, including low platelets and prolonged clotting times, are common even without bleeding symptoms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multivariate approach to exploring interrelationships among milk fatty acids across ruminant species.

Journal of dairy science·2026
Same author

Growth performance, proximate composition and fatty acid profile of black soldier fly larvae reared on two grape pomace varieties.

Animal : an international journal of animal bioscience·2024
Same author

AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by <i>rfaP</i> and <i>ybaT</i> deletion.

Gut microbes·2024
Same author

Effect of different diet composition on the fat profile of two different black soldier fly larvae populations.

Animal : an international journal of animal bioscience·2024
Same author

Candidacy and long-term outcomes of subcutaneous implantable cardioverter-defibrillators in current practice in patients with hypertrophic cardiomyopathy.

International journal of cardiology·2024
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024

Area of Science:

  • Coagulation disorders
  • Sepsis
  • Intensive Care Unit (ICU) medicine

Context:

  • Sepsis is a life-threatening condition associated with dysregulated host response.
  • Coagulation abnormalities are frequently observed in sepsis patients.
  • Understanding these disorders is crucial for patient management in the ICU.

Purpose:

  • To investigate the spectrum and frequency of coagulation disorders in sepsis patients.
  • To analyze the relationship between coagulation parameters, shock, and hemorrhagic manifestations.
  • To determine the impact of coagulation disturbances on mortality in sepsis.

Summary:

  • A retrospective study analyzed coagulation profiles of 61 sepsis patients in the ICU.
  • Abnormal prothrombin time (81%) and thrombocytopenia (73%) were prevalent.

Related Experiment Videos

  • Coagulation abnormalities were more severe in patients with shock and often indicated intravascular coagulation (53%).

    • Impact:

    • Coagulation disturbances are common in sepsis, often subclinical.
    • Shock significantly exacerbates coagulation abnormalities in sepsis.
    • Despite frequent disturbances, no direct correlation with mortality was found in this study.