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Urine culture sensitivity pattern in a private laboratory setup
A V Ramaprasad1, N Jayaram, G Nageshappa
1Anand Diagnostic Laboratory, Bangalore.
Indian Journal of Pathology & Microbiology
|April 1, 1993
Summary
A two-year study found 24.15% of urine cultures were infected, with E. coli most common. Ciprofloxacin and Norfloxacin showed promise against resistant urinary tract infection strains.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Urinary tract infections (UTIs) are common, necessitating ongoing surveillance of causative pathogens and their antibiotic resistance patterns.
- Understanding local microbial epidemiology is crucial for effective treatment strategies.
Purpose of the Study:
- To analyze the prevalence and causative agents of UTIs in a specific clinical setting.
- To evaluate the antibiotic sensitivity patterns of common uropathogens.
- To identify effective antibiotics for treating resistant UTI strains.
Main Methods:
- Analysis of 6163 urine samples cultured over a two-year period.
- Identification of bacterial pathogens and assessment of their antibiotic susceptibility.
- Statistical analysis of infection rates and resistance patterns.
Main Results:
- A significant infection rate of 24.15% (1488/6163) was observed in urine cultures.
- Escherichia coli (E. coli) was the predominant pathogen (61.40%), followed by Klebsiella (17.1%).
- Ciprofloxacin and Norfloxacin demonstrated favorable sensitivity profiles, while Cloxacillin, Colistin, and Lincomycin showed limited efficacy.
Conclusions:
- The study highlights the prevalent pathogens causing UTIs and their antibiotic resistance trends in the analyzed population.
- Emergence of multi-drug resistant strains, even to newer antibiotics, is a concern.
- Ciprofloxacin and Norfloxacin are recommended as effective treatment options for UTIs caused by susceptible organisms.