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Related Experiment Videos

Urine culture sensitivity pattern in a private laboratory setup

A V Ramaprasad1, N Jayaram, G Nageshappa

  • 1Anand Diagnostic Laboratory, Bangalore.

Indian Journal of Pathology & Microbiology
|April 1, 1993
PubMed
Summary

A two-year study found 24.15% of urine cultures were infected, with E. coli most common. Ciprofloxacin and Norfloxacin showed promise against resistant urinary tract infection strains.

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Urinary tract infections (UTIs) are common, necessitating ongoing surveillance of causative pathogens and their antibiotic resistance patterns.
  • Understanding local microbial epidemiology is crucial for effective treatment strategies.

Purpose of the Study:

  • To analyze the prevalence and causative agents of UTIs in a specific clinical setting.
  • To evaluate the antibiotic sensitivity patterns of common uropathogens.
  • To identify effective antibiotics for treating resistant UTI strains.

Main Methods:

  • Analysis of 6163 urine samples cultured over a two-year period.
  • Identification of bacterial pathogens and assessment of their antibiotic susceptibility.

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  • Statistical analysis of infection rates and resistance patterns.
  • Main Results:

    • A significant infection rate of 24.15% (1488/6163) was observed in urine cultures.
    • Escherichia coli (E. coli) was the predominant pathogen (61.40%), followed by Klebsiella (17.1%).
    • Ciprofloxacin and Norfloxacin demonstrated favorable sensitivity profiles, while Cloxacillin, Colistin, and Lincomycin showed limited efficacy.

    Conclusions:

    • The study highlights the prevalent pathogens causing UTIs and their antibiotic resistance trends in the analyzed population.
    • Emergence of multi-drug resistant strains, even to newer antibiotics, is a concern.
    • Ciprofloxacin and Norfloxacin are recommended as effective treatment options for UTIs caused by susceptible organisms.