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Related Experiment Videos

Observations with high-dose Mydocalm therapy

A M Kiss1, J Martos

  • 1Sopron, State Sanatorium, Hospital for Balneotherapy, Balf, Hungary.

Therapia Hungarica (English Edition)
|January 1, 1993
PubMed
Summary

Coated Mydocalm (tolperisone hydrochloride) combined with physiotherapy accelerates pain relief and reduces muscle spasms in locomotor diseases. This adjuvant therapy is recommended for conditions involving muscle hypertonia and contracture.

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Area of Science:

  • Pharmacology
  • Physical Medicine and Rehabilitation

Background:

  • Muscular hypertonia, spasticity, and contracture are common in locomotor diseases.
  • Physiotherapy is a standard treatment for these conditions.
  • Adjuvant pharmacological treatments may improve therapeutic outcomes.

Purpose of the Study:

  • To evaluate the efficacy of coated Mydocalm as an adjunct to physiotherapy.
  • To compare outcomes in patients receiving Mydocalm plus physiotherapy versus physiotherapy alone.

Main Methods:

  • A comparative study involving 94 patients with locomotor diseases.
  • One group received coated Mydocalm (150 mg three times daily for 3 weeks) with physiotherapy.
  • The control group received physiotherapy solely.

Main Results:

  • Patients receiving Mydocalm as an adjuvant showed faster alleviation of pain.
  • Moderation of muscular hypertonia and spasm was observed in a shorter period with adjuvant Mydocalm.
  • No significant adverse events were mentioned.

Conclusions:

  • Coated Mydocalm is recommended as an effective adjuvant to complex therapy for locomotor diseases.
  • Recommended dosage for adjuvant therapy is 300-450 mg daily.
  • Mydocalm aids in treating conditions characterized by muscular hypertonia, spasticity, and contracture.

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