Related Experiment Videos
[Current status of experimental transplantation of allogeneic extremities]
R Büttemeyer1, N F Jones, P Vogt
1Division of Plastic and Reconstructive Surgery, University of California, Los Angeles.
The experimental and clinical progress in the field of immunosuppression, microsurgical replantation and macro-replantation provides a basis for the allotransplantation of whole limbs or anatomical segments. Possible indications would be clinically: Posttraumatic and tumor-induced defects, as well as congenital and infectious mutilations. Specific immunological problems of rejection under different immunosuppressive regimens and future methods for the induction of immune tolerance are discussed.
The experimental and clinical progress in the field of immunosuppression, microsurgical replantation and macro-replantation provides a basis for the allotransplantation of whole limbs or anatomical segments. Possible indications would be clinically: Posttraumatic and tumor-induced defects, as well as congenital and infectious mutilations. Specific immunological problems of rejection under different immunosuppressive regimens and future methods for the induction of immune tolerance are discussed.