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Updated: Jul 30, 2026

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Published on: July 12, 2011
A coagulopathy of the owl monkey (Aotus trivirgatus) associated with high antithrombin III activity
Abstract:
The species-associated coagulopathy of the owl monkey (Aotus trivirgatus) was shown to be caused by a high level of circulating anticoagulant, antithrombin III, in approximately 4-6 times the activity in which the same anticoagulant is found in man or the rhesus monkey (Macaca mulatta). The survival of the owl monkey in the presence of this added biological risk is an interesting and enigmatic observation. Treatment with protamine, prednisone, or estradiol did not alter the activity of circulating anticoagulant.
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