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Related Experiment Videos

Effect of training on eccentric exercise-induced muscle damage

C D Balnave1, M W Thompson

  • 1Department of Biological Sciences, Faculty of Health Sciences, University of Sydney, Lidcombe, New South Wales, Australia.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|October 1, 1993
PubMed
Summary

Eccentric exercise causes muscle damage and soreness. Training reduces these effects, but muscle function can be impaired even without significant muscle damage indicators.

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Area of Science:

  • Exercise Physiology
  • Muscle Physiology
  • Sports Medicine

Background:

  • Eccentric muscle contractions are known to induce delayed onset muscle soreness (DOMS).
  • High muscle tensions during eccentric exercise are hypothesized to cause muscle damage, leading to DOMS.

Purpose of the Study:

  • To investigate the effects of an 8-week eccentric exercise training regimen on muscle function, serum muscle damage indicators, and DOMS.
  • To examine the time course of adaptations in response to repeated eccentric exercise.

Main Methods:

  • Participants underwent a 40-minute eccentric walking protocol on a treadmill (25% gradient, 6.4 km/h) weekly for 8 weeks.
  • Muscle function (fatigability, maximal voluntary contraction force), DOMS, and serum creatine kinase and myoglobin levels were measured.

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Main Results:

  • Serum creatine kinase and myoglobin showed a delayed increase post-exercise, indicating muscle damage.
  • Eccentrically trained muscles exhibited low-frequency fatigue and reduced maximal voluntary contraction force immediately post-exercise.
  • Training led to reductions in DOMS, serum muscle protein response, and muscle function impairment, but with different adaptation timelines.

Conclusions:

  • Repeated eccentric exercise training attenuates DOMS and associated muscle damage markers.
  • Muscle function can be impaired following eccentric exercise even in the absence of significant increases in serum muscle damage indicators.
  • The distinct time courses of adaptation suggest differential responses of muscle damage and function to training.