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Granulomatous enteritis and cutaneous arteritis in a horse
P R Woods1, R G Helman, D G Schmitz
1Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843.
Journal of the American Veterinary Medical Association
|December 1, 1993
Summary
A Quarter Horse mare experienced weight loss, anemia, and skin ulcers. Necropsy revealed granulomatous enteritis, suggesting similarities to human regional enteritis.
Area of Science:
- Veterinary Medicine
- Equine Health
- Gastroenterology
Background:
- A 5-year-old Quarter Horse mare presented with a two-month history of progressive weight loss.
- The mare was clinically anemic, in poor body condition, and exhibited cutaneous ulcerations on the muzzle and distal limbs.
Observation:
- Histological examination of a rectal biopsy showed lymphoplasmacytic infiltrate in the lamina propria mucosa.
- A glucose absorption test indicated malabsorption.
- Biopsy of cutaneous lesions revealed arteritis and immunoglobulin deposition at the basement membrane.
Findings:
- The horse was treated with prednisone without improvement and was humanely destroyed.
- Necropsy confirmed granulomatous enteritis.
Implications:
- This case highlights an unusual combination of clinical signs in a horse.
- The findings suggest potential similarities between equine granulomatous enteritis and regional enteritis in humans, warranting further investigation.