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Hypertensive effect of polyunsaturated dietary fat
L N Kaufman1, M M Peterson, S M Smith
1Department of Physiology, Michigan State University, East Lansing 48824.
Abstract:
Male Sprague-Dawley rats were fed a diet high in either saturated fat (lard) or polyunsaturated fat (corn oil) beginning at 10 weeks of age. After 10 weeks of diet treatment, blood pressure (BP) was 17% higher in rats fed saturated fat and 8% higher in rats fed polyunsaturated fat than in rats fed a low-fat control diet. Rats fed the lard diet became obese, and their fasting insulin levels were elevated (38% above control). These data demonstrate that both saturated and polyunsaturated dietary fats induce hypertension.
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