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Huntington's disease and low tryptophan diet
1Royal Children's Hospital, Melbourne, Australia.
Medical Hypotheses
|October 1, 1993
Summary
Abnormal tryptophan metabolism may cause Huntington's disease brain damage. A case study suggests a low tryptophan diet might improve outcomes, potentially delaying onset or reducing symptom severity.
Area of Science:
- Neuroscience
- Metabolic disorders
- Neurodegenerative diseases
Background:
- Huntington's disease (HD) is a neurodegenerative disorder.
- Abnormal tryptophan metabolism and quinolinic acid are implicated in HD pathogenesis.
- The exact mechanisms causing brain damage in HD require further elucidation.