Effect of the cold pressor test in healthy and hyperacid subjects

The aim of this study was to estimate the effects of the cold pressor test (CPT) on hemodynamic changes and to analyze the differences in the changes between normal and hyperacid subjects. Twelve healthy volunteers and 12 hyperacid patients were studied. The different hemodynamic parameters (basic impedance, ZO; heart rate, HR; systolic and diastolic blood pressure, RRs and RRd; ventricular ejection time, VET; stroke volume, SV; cardiac output, CO; rate-pressure-product, RPP) were measured and calculated with the impedance cardiographic method (ICG). The changes of hemodynamic parameters (HR, RRs, RRd, VET, SV, CO, RPP) were well-recorded by this method. The data were analyzed with unpaired t-tests and the multivariate statistical method, pattern recognition by independent multicategory analysis (PRIMA). There were significant differences in changes of ZO, HR (P < 0.05), RRs, RRd, SV, CO and VET (P < 0.01) and subjects in the normal and hyperacid groups could be well separated by the PRIMA method.