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Updated: Aug 14, 2026

Cell-based Calcium Assay for Medium to High Throughput Screening of TRP Channel Functions using FlexStation 3
Published on: August 17, 2011
[Hypercalcemia as incidental finding--what should be done?]
1Département de médecine interne, Service de médecine interne A CHUV, Lausanne.
Abstract:
The discovery of a hypercalcemia validated by exclusion of hemoconcentration and follow-up calcium determinations opens the differential diagnosis of a malignancy and of hyperthyroidism whereas drug-induced causes can be recognized easily. A single determination of plasmatic parathyroid hormone (PTH) allows to safely distinguish between PTH-induced or PTH-independent, most often tumor-associated hypercalcemia. In both instances the patient may be free of symptoms particularly the very old one. Therapeutic measures are indicated in both instances: Treatment of malignancy-associated hypercalcemia is clinically effective and treatment of asymptomatic hyperthyroidism is likewise recommended, mainly to preserve bone mass and cerebral performance.
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