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Burkitt's lymphoma in the Sudan
African Journal of Medicine and Medical Sciences
|June 1, 1976
Summary
This study examined 29 cases of Burkitt's lymphoma in Sudanese children between 1962-73. Findings reveal a strong geographical link between this childhood cancer and endemic malaria regions.
Area of Science:
- Oncology
- Epidemiology
- Pediatric Hematology-Oncology
Background:
- Burkitt's lymphoma is a childhood cancer with distinct epidemiological patterns.
- Understanding its prevalence and geographical distribution is crucial for public health initiatives.
Purpose of the Study:
- To describe the clinical and histological features of Burkitt's lymphoma cases in Khartoum, Sudan.
- To investigate the geographical distribution of Burkitt's lymphoma in relation to malaria endemicity.
Main Methods:
- Retrospective analysis of 29 histologically confirmed Burkitt's lymphoma cases diagnosed between 1962 and 1973.
- Correlation of tumor geographical distribution with malaria endemicity data.
Main Results:
- Burkitt's lymphoma constituted 20% of childhood lymphomas.
- The average age was 6.8 years, with a male to female ratio of 3.8:1.
- Clinical, anatomical, and histological features aligned with existing literature.
- Tumor distribution strongly correlated with holo- or hyperendemic malaria zones.
Conclusions:
- The findings support the association between Burkitt's lymphoma and malaria in Sudan.
- Further research into the etiological link between malaria and Burkitt's lymphoma is warranted.