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Ovulation induction with GnRH agonist and human menopausal gonadotropins: response in patients with one versus two
A S Penzias1, J N Gutmann, F N Shamma
1Yale University School of Medicine, Department of Obstetrics & Gynecology, New Haven, Connecticut.
Objective:
To examine the effect of oophorectomy on response to gonadotropin releasing hormone-agonist/human menopausal gonadotropin (GnRH-a/hMG) for in vitro fertilization (IVF).
Design:
Retrospective review.
Setting:
Tertiary care academic institution.
Patients:
Ninety-one infertile patients undergoing IVF. Eighty-four women had two ovaries and seven had only one ovary.
Results:
There was no difference observed between women with one versus two ovaries with regard to response to medications, hormone production, number of oocytes retrieved and fertilized, or the number of embryos cleaved and transferred.
Conclusion:
Women with only one ovary are at no reproductive disadvantage when undergoing ovulation induction for IVF.