Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Definition of "salt sensitivity"]

C Ummenhofer1, R Kluthe

  • 1Deutsche Akademie für Ernährungsmedizin, Freiburg.

Deutsche Medizinische Wochenschrift (1946)
|January 21, 1994
PubMed
Summary

The definition of salt sensitivity lacks consistency across studies. Current evidence is insufficient to differentiate between salt-sensitive and salt-insensitive individuals, suggesting hypertensives should not avoid reducing salt intake.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of various rapid chloride tests for assessing urinary NaCl excretion.

Annals of nutrition & metabolism·2001
Same author

International Symposium on Sodium and Hypertension. Results of randomized trials.

The Clinical investigator·1994
Same author

[Sodium administration and hypertension. German Academy of Nutrition Medicine].

Medizinische Monatsschrift fur Pharmazeuten·1994
Same author

[Table salt and blood pressure].

Deutsche medizinische Wochenschrift (1946)·1993
Same author

[Hypertension].

Bibliotheca nutritio et dieta·1992
Same author

Effect of amino acid based dialysis solution on peritoneal permeability and prostanoid generation in patients undergoing continuous ambulatory peritoneal dialysis.

American journal of nephrology·1992

Area of Science:

  • Cardiovascular Research
  • Clinical Nutrition
  • Hypertension Studies

Context:

  • The definition and measurement of salt sensitivity have varied significantly in clinical research.
  • Previous studies (1978-1992) employed diverse methodologies to assess salt sensitivity in both normotensive and hypertensive individuals.

Purpose:

  • To critically analyze the various definitions and experimental approaches used to define "salt sensitivity" in published clinical studies.
  • To evaluate the evidence base for distinguishing between salt-sensitive and salt-insensitive subjects.

Summary:

  • A review of 32 studies published between 1978 and 1992 revealed inconsistent experimental designs for determining salt sensitivity.
  • Three main study types were identified based on sodium intake manipulation: low-to-high, high-to-low, and randomized sequences.
  • The analysis concluded that current evidence is insufficient to reliably differentiate salt-sensitive from salt-insensitive individuals.

Impact:

  • Challenges the established concept of distinct salt sensitivity categories in hypertension research.
  • Suggests that individuals with hypertension should not be discouraged from reducing their sodium chloride intake based on current evidence.
  • Highlights the need for standardized methodologies in future salt sensitivity research.

Related Experiment Videos