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Characterization of the trehalose 6,6'-dimycolate surface monolayer by scanning tunneling microscopy
R W Schabbing1, A Garcia, R L Hunter
1Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30322.
Infection and Immunity
|February 1, 1994
Abstract:
The toxicity of trehalose 6,6'-dimycolate (TDM), a glycolipid of mycobacteria, requires presentation as a surface monolayer. Our model of the structure of the TDM monolayer was confirmed and extended by scanning tunneling microscopy. It consists of linear arrays with a periodicity of approximately 90 A (9 nm) that clustered in groups of four to form secondary structures with a periodicity of 360 A (36 nm).