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Antiphospholipid syndrome in pregnancy: a diagnostic dilemma
F L Clark1, P Greenwood, P J Forster
1James Paget Hospital, Great Yarmouth, Norfolk, United Kingdom.
Objective:
To present a case of severe pre-eclampsia in which diagnosis of the antiphospholipid syndrome was made after delivery, and to discuss pointers to the diagnosis.
Clinical Features:
A 32-year-old woman in her second pregnancy presented at 32 weeks' gestation with severe pre-eclampsia. Her persisting severe postpartum illness was investigated. The presence of anticardiolipin antibodies and lupus anticoagulant led to the diagnosis of antiphospholipid syndrome.
Intervention And Outcome:
Induction of labour was successful, with delivery of a healthy baby girl. The patient made a full recovery after treatment with corticosteroids and warfarin.
Conclusion:
The antiphospholipid syndrome should be considered in cases of severe early pre-eclampsia.

