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Updated: Aug 12, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 18, 2014
[Double infection of the lung with Pneumocystis carinii and Cryptococcus neoformans in an AIDS patient]
H Albrecht1, H J Stellbrink, S Fenske
1Medizinische Kernklinik und Poliklinik, Universitätskrankenhaus Eppendorf, Hamburg.
Abstract:
A 25-year old HIV-1-positive hemophiliac was admitted with fever, cough, exertional dyspnea and pleuritic chest pain. Chest x-ray showed diffuse bilateral infiltrates with a left sided nodular consolidation. Pneumocystis-carinii-pneumonia was suspected and diagnosed by broncho-alveolar lavage. With therapy the diffuse infiltrates improved, but the nodule and the symptoms failed to resolve. A fine-needle aspiration of the nodule revealed concurrent cryptococcosis. Treatment with fluconazole resulted in complete resolution of symptoms. Details of the case are presented and clinical implications are discussed.
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