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Related Experiment Videos

Scleroderma and the carcinoid syndrome

R C Ratnavel1, N P Burrows, R J Pye

  • 1Department of Dermatology, Addenbrooke's Hosital, Cambridge, UK.

Clinical and Experimental Dermatology
|January 1, 1994
PubMed
Summary

This study reports a carcinoid syndrome case with scleroderma, potentially halted by combined treatment. Tryptophan and serotonin metabolism impairment may link carcinoid skin fibrosis to scleroderma pathogenesis.

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Area of Science:

  • Medical Science
  • Oncology
  • Dermatology

Background:

  • Carcinoid syndrome can present with scleroderma.
  • Skin fibrosis is a key feature in some carcinoid syndrome cases.
  • Tryptophan and serotonin metabolism alterations are implicated in carcinoid-related fibrosis.