Related Experiment Videos
Use of the regressive models in linkage analysis of quantitative traits
1Unité de Recherche de Génétique des Maladies Humaines (INSERM U.358), Centre d'Etude du Polymorphisme Humain, Paris, France.
Genetic Epidemiology
|January 1, 1993
Abstract:
Use of the regressive models to account for residual familial correlations in linkage analysis of complex quantitative traits can increase the power to detect linkage. This is especially observed when the effect of the gene to be mapped is small or when the residual correlations are substantial.