Related Experiment Video
Updated: Aug 12, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
The parallel Lack anaesthetic breathing system
The parallel Lack system, a modified Mapleson A circuit, effectively prevents rebreathing during spontaneous ventilation in lung models, volunteers, and patients. Its performance is comparable to the Magill attachment, ensuring safe anesthesia delivery.
Area of Science:
- Anesthesiology
- Respiratory Physiology
Background:
- The Mapleson A system is a common anesthetic circuit.
- Modifications aim to improve performance and safety.
Purpose of the Study:
- To evaluate the parallel Lack system, a novel Mapleson A modification.
- To determine its efficacy in preventing rebreathing during spontaneous ventilation.
Main Methods:
- Assessed fresh gas flow requirements to prevent rebreathing.
- Utilized a lung model, conscious volunteers, and anesthetized patients.
- Defined rebreathing using ventilation changes, end-expired CO2, and inspired CO2 tension.
Main Results:
- Rebreathing onset occurred at a fresh gas flow to minute ventilation ratio (VF/VE) of approximately 0.75 in lung models and volunteers.
- Results were comparable to the Magill attachment.
- The parallel Lack system demonstrated Mapleson A functionality in anesthetized patients.
Conclusions:
- The parallel Lack system functions as a Mapleson A circuit.
- It effectively prevents rebreathing during spontaneous ventilation.
- Breathing resistance is comparable to the Magill system.
Related Concept Videos
Inhalational Anesthetics: Overview
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Cardiopulmonary Resuscitation II: ACLS Airway Management

