Related Experiment Video
Updated: Jul 31, 2026

Femoral Bone Marrow Aspiration in Live Mice
Published on: July 5, 2014
Regional versus general anesthesia for bone marrow harvesting
1Department of Anaesthesiology, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
Regional anesthesia for bone marrow harvesting required less transfused blood and postoperative analgesia compared to general anesthesia. Both anesthesia types were safely administered, warranting further investigation into their equivalence.
Area of Science:
- Anesthesiology
- Hematology
- Transplantation Medicine
Background:
- Bone marrow harvesting is a critical procedure in transplantation.
- Anesthesia choice impacts patient outcomes and resource utilization.
Purpose of the Study:
- To compare the efficacy and safety of regional versus general anesthesia for bone marrow harvesting.
- To evaluate perioperative outcomes, including blood transfusion, analgesia, and hospitalization length.
Main Methods:
- Retrospective study of 162 bone marrow donors (63 heterologous, 99 autologous).
- Review of anesthesia records and patient charts from 1986 to 1990.
- Comparison of outcomes between patients receiving regional and general anesthesia.
Main Results:
- Regional anesthesia was associated with reduced perioperative blood transfusion requirements despite greater marrow aspiration.
- Patients under regional anesthesia needed less postoperative pain management.
- No significant differences were observed in hospitalization duration or perioperative colloid administration.
Conclusions:
- Both regional and general anesthesia are viable options for bone marrow harvesting.
- Further research is recommended to definitively establish the equivalence of regional and general anesthesia in this context.
More Related Videos
04:24Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography
Published on: November 22, 2017
09:57Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
Related Concept Videos
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia