Related Experiment Videos
[Pseudomyxoma peritonei. Apropos of 19 cases]
F Delinière1, J P Arnaud, C Casa
1Service de Chirurgie Viscérale, CHU, Angers.
Journal De Chirurgie
|March 1, 1993
Summary
Pseudomyxoma peritonei, a rare condition, often presents insidiously with symptoms like ascites and abdominal pain. Surgical treatment offers a 5-year survival rate of 65%, though recurrence is common.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Pseudomyxoma peritonei (PMP) is a rare clinical condition characterized by mucinous ascites.
- The disease often originates from appendiceal or ovarian mucinous tumors.
Purpose of the Study:
- To review the clinical presentation, diagnosis, treatment, and outcomes of PMP patients.
- To evaluate the long-term survival rates and recurrence patterns following surgical intervention.
Main Methods:
- Retrospective analysis of 19 patients diagnosed with PMP between 1971 and 1991.
- Diagnosis aided by imaging (scan) and serum angiotensin-converting enzyme (ACE) levels.
- All patients underwent surgical treatment.
Main Results:
- The predominant symptoms included ascites, abdominal mass, distension, and pain.
- The primary mucosecreting tumors were appendiceal (12 cases) and ovarian (11 cases).
- Histology was benign in 17 out of 19 patients; 10 patients experienced recurrence post-surgery.
- Global survival rates were 65% at 5 years and 49% at 10 years.
Conclusions:
- PMP presents insidiously, with diagnosis often requiring imaging and biochemical markers.
- While surgery is the primary treatment, recurrence is frequent, impacting long-term survival.
- Further research into improved management strategies for PMP is warranted.